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Common Gastrointestinal Concerns Both dual and triple agonists share a class-wide side effect profile dominated by gastrointestinal issues, primarily: Nausea Diarrhea or Constipation Vomiting These effects are dose-related and typically peak during the dose-escalation phase
PMID 14768020
they may suggest minor schedule adjustments to prevent dose clustering
Unlike conventional daily regimens, its once-weekly administration fosters adherence while maintaining consistent glycemic modulation
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