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But the gap between "berberine has some evidence when swallowed at 1,500 mg" and "a patch with 8.75 mg of berberine will help you lose weight through your skin" is a canyon, and the marketing fills that canyon with aspiration rather than data
It also mimics the action of the natural GLP-1 hormone by increasing insulin release and delaying the stomach emptying
Potential for unknown long-term side effects There is insufficient data on the long-term safety and efficacy of microdosing protocols
Conclusion Liraglutide was associated with the highest risk of clinically relevant cholelithiasis than semaglutide, and dulaglutide in patients with T2D
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