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Research uses 250-1,000mg/day depending on the goal, with most skin-focused studies clustering around 500mg over 8-12 weeks
doi: 10.1111/dom.13484 2 BethelM
The efficacy of canagliflozin in diabetes subgroups stratified by data-driven clustering or a supervised machine learning method: a post hoc analysis of canagliflozin clinical trial data
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