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Pain often returns because the underlying driverssuch as inflammation, tissue injury, nervous system sensitization, or metabolic dysfunctionwere never corrected

Prior to the relatively recent description of the microbiota as a potent modulator of a range of physiological and psychological factors, even controversially termed as an extra organ (as discussed by Riccio and Rossano, 2020), the GIT bacteria were largely ignored, even in studies of digestion

It helps reduce redness because of its anti-inflammatory qualities

The absence of a plausible interaction mechanism no CYP450 involvement, no blood-sugar effects, and poor oral bioavailability means the theoretical risk is low