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For the researchers, this finding raised questions about implications for aging, frailty and fitness in the long term

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Dietary recommendations include: Eating smaller, more frequent meals rather than large portions, which can overwhelm the slowed digestive system Increasing dietary fibre gradually through fruits, vegetables, whole grains, and legumes to support regular bowel movements and potentially benefit diverticular disease Maintaining adequate hydration aim for 6-8 glasses of water daily, particularly important if experiencing diarrhoea or constipation Limiting high-fat, fried, and spicy foods that may exacerbate nausea and delayed gastric emptying Avoiding carbonated beverages if experiencing bloating or discomfort Eating slowly and chewing thoroughly to aid digestion Lifestyle measures that support gastrointestinal health include regular physical activity, which promotes gut motility and can help prevent constipation

Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study