A 2025 systematic review mapped weight change after stopping anti-obesity medicines across 11 RCTs
Although less common, some people experience more severe adverse reactions to topiramate, such as: Kidney stones , hard deposits of minerals in the kidneys that can cause back or flank (side) pain, nausea, vomiting, and bloody, cloudy, or smelly urine Metabolic acidosis, a condition in which too much acid is in the bloodstream, leading to irregular heartbeat, fatigue, and confusion
If you are in the first four to six weeks on a starting dose, you may not have given the medication enough time or dose to show meaningful effects
Science-backed formulation May help curb post-meal glucose spikes Vegetarian and non-GMO Expensive Research is still limited Requires refrigeration Formulation Glucose Control is built around a five-strain probiotic blend plus a prebiotic fiber, making it technically a synbiotic, not a probiotic alone