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Cost-benefit analysis helps assess whether continued annual therapy provides sufficient value relative to investment

Mediterranean-style diets emphasizing olive oil, fatty fish, vegetables, and whole foods reduce systemic inflammation that can impair healing

Mechanisms underlying neuroprotection include enhanced cerebral angiogenesis supporting tissue oxygenation, anti-inflammatory effects reducing secondary injury, antioxidant activity limiting free radical damage, and modulation of neurotransmitter systems including the dopamine/glutamate/NO system

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