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In the primary Phase 2 clinical trial published in the New England Journal of Medicine (Jastreboff et al., 2023), retatrutide was studied across several dose levels, including: 1 mg (low dose) 4 mg (mid dose) 8 mg (higher dose) 12 mg (highest dose) These doses were administered as once-weekly subcutaneous injections

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Side effects and safety considerations The most common side effects of GLP-1 medications are gastrointestinal and include nausea, vomiting, diarrhoea, constipation, and abdominal discomfort

Patients using PlexusDx compounded semaglutide can expect the same appetite reduction, metabolic effects, and weight loss trajectory as those using Ozempic or Wegovy