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Elimination is slow so it is recommended to take precautions in patients with severe liver impairment.52 The administration of pioglitazone and rosiglitazone for the treatment of NAFLD (presumably without cirrhosis) with or without DM has yielded conflicting results
Because these medications are FDA approved weight loss pills , they are prescribed only after a medical evaluation to ensure safety and effectiveness
J Biol Chem 267: 21432-21437, 1992
However, whether or not albuminuria is a clinically relevant renal outcome remains unclear
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