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GLP-1 medicine improves liver health GLP-1 medicine improves liver health independent of weight loss Researchers have found that semaglutide the active ingredient in popular weight loss drugs that mimic the gut hormone GLP-1 acts directly on a subset of liver cells to improve organ function and does so independently of weight loss

Most researchers anticipate that long-term treatment will be necessary to maintain results, similar to how blood pressure medication must be continued to maintain blood pressure control

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Weight loss with tirzepatide According to one double-blind, randomized, controlled trial published in The New England Journal of Medicine , different dosages of tirzepatide all led to a meaningful reduction in body weight over 72 weeks when combined with a reduced-calorie diet and 150 minutes of exercise per week