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SKU: 40475046217
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USD24.37 USD71.37

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Description

In agreement with our previously detected acute cAMP defect in beta cell -arrestin 2 KO islets, this experiment revealed a small but significant reduction in Emax, with no change in logEC50, for exendin-4-induced GLP-1R signalling at the plasma membrane in -arrestin 2 KD compared with control cells, with no changes associated with the degree of endosomal signalling (Fig

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