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Clinical trials and observational studies have demonstrated that nutritional interventions focusing on this pathwayparticularly using methylcobalamin and folinic acidmay lead to measurable improvements in behaviour, communication, and cognitive function for some children with autism, especially those with evidence of methylation pathway dysfunction

Medical Disorders People who have liver disorders often have difficulty storing vitamin B12, so it is quickly absorbed into the body rather than stored for later use

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The kidneys function as the primary regulatory organ for maintaining systemic carnitine homeostasis and controlling elimination processes