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Interestingly, multiple transcription factors, such as Myc, Wnt, and hypoxia inducible factors, can cause a transcriptional increase of one or more PDK isoforms in a cancer cell
Protein intake is particularly important, as the thermic effect of protein (the energy required to digest and process it) is higher than that of carbohydrates or fats, contributing to heat production
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Defective mitochondrial DNA homeostasis in the substantia nigra in Parkinson disease
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