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MutationTaster2: mutation prediction for the deep-sequencing age
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Systematic substitution of each residue in the sequence with Ala enables the identification of critical amino acids governing protein bioactivity
Safety and Tolerability: What Is and Isnt Known Safety is often where the two compounds are oversold as side-effect-free. The accurate picture is narrower: both look well tolerated in the limited settings that have been studied, and both lack long-term human safety data
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