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If there has been a prolonged interruption of several weeks, your clinician may recommend restarting at a lower dose initially to minimise gastrointestinal side effects such as nausea
This structural damage cannot be reversed by thawing, and the medication loses its ability to bind effectively to GIP and GLP-1 receptors, compromising its glucose-lowering and weight-reducing effects
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In addition to supporting weight loss and metabolic health, some GLP-1s are used to reduce cardiovascular risk in people with type 2 diabetes and heart disease, and studies are exploring potential benefits in fatty liver disease and kidney health
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