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Background GLP-1R agonists protect the blood-brain barrier (BBB): These drugs help maintain the integrity of the BBB by preventing tight junction degradation, which can reduce the risk of neuroinflammation and cognitive decline
Similarly, elevated IL-1 levels have been observed in elderly patients with mild cognitive impairment compared with healthy controls [10]
Your healthcare provider may consider adjusting your titration schedule or maintaining a lower dose if headaches are problematic
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