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Moderate ROS levels stimulate growth and division, but excessive accumulation disrupts redox balance, creating stress [38] that contributes to age-related decline in both oocyte quality and quantity [34, 35]
Clinical trial data from the SURMOUNT-1 study demonstrated that patients achieved maximum weight loss at approximately 72 weeks (18 months), with average reductions of 15.0% (5 mg), 19.5% (10 mg), and 20.9% (15 mg) of initial body weight
I.NeubigR
The reference currently listed for Chen et al
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