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doi: 10.1182/blood.2024025246 35 YangYLinYHanZWangBZhengW
In MS models, AST has demonstrated protective effects against demyelination by preserving oligodendrocyte viability and reducing inflammatory cytokine expression, both of which are critical in maintaining myelin sheath integrity ( Table 3, which highlights differences in study design, dosing regimens, and outcome measures
Inhibition of oxidative metabolism to target cancer cell proliferation using various inhibitors has shown promise in both human and murine preclinical models 77
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