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This was demonstrated in two randomised controlled trials (RCTs) that showed a decrease in epicardial adipose tissue in patients with T2D and obesity on liraglutide and exenatide according to echocardiography and cardiac MRI

At the same time, our results clearly indicate that even a small concentration of selenium (10 mg/L) can have a measurable effect on ROS production in the cells, which indicated high enzymatic activity of GPx

Weinblatt ME, Keystone EC, Furst DE, Moreland LW, Weisman MH, Birbara CA, et al