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Research supports that combining the piperine in black pepper with the curcumin in turmeric enhances curcumin absorption by up to 2,000% ( One study showed that adding 20 mg of piperine to 2 grams of curcumin increased its absorption significantly ( There are currently two theories on how this works
Additional reference Eilat-Adar S, et al., Nutritional Recommendations for Cardiovascular Disease Prevention
The pioneering 2017 Phase 1b trial of setmelanotide (mentioned above), while providing a critical proof-of-concept for weight loss in a small cohort of heterozygous carriers, was primarily designed as an exploratory study
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