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In breast cancer, where EGFR inhibitors such as erlotinib are being used to inhibit the EGFR signaling pathway, IGF-1R confers resistance by forming one half of a heterodimer (see the description of EGFR signal transduction in the erlotinib page), allowing EGFR signaling to resume in the presence of a suitable inhibitor

Eating past this point almost guarantees bloating and nausea later

These ROS overwhelm the antioxidant defenses of cancer cells, including glutathione (GSH), superoxide dismutase (SOD), and catalase

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