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There is some early evidence from clinical trials that at least some of this is true

We envision that this new GSH probe will enable unprecedented opportunities to study GSH dynamics and transportation and revolutionize our understanding of the physiological and pathological roles of GSH in living cells

It has also been suggested that DPP-4 might be secreted into the interstitial spaces within the islets (100) and, accordingly, DPP-4 activity can be measured in the media of human islet incubations (101), but whether this is simple shedding of membrane-associated DPP-4 or regulated secretion is not known

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