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Supplements are also playing an increasingly recognized role

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Moreover, the comparison between DPP-4 inhibitors and placebo demonstrated no difference in their risk for MACE (RR = 0.99, 95% CI 0.931.06)

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Mitochondrial dysfunction in surrounding brain tissue leads to the release of damage-associated molecular patterns (DAMPs) that bind to microglial receptors and induce pro-inflammatory pathways (137)

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