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In pharmaceutical peptide development, 2D NMR plays a major role in determining disulfide bond arrangements, evaluating cyclic peptide conformations, characterizing helical or beta-sheet secondary structures during lead optimization, and identifying aggregation-sensitive regions important for formulation studies
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Fogarasi A, Gonzalez K, Dalamaga M, Magkos F
GLP-1 analogues have been shown to have cardiovascular benefits and are generally safe for use in individuals with a history of heart disease
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