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The involvement of GSH in the reduction of Prx6type peroxiredoxins appears not to be restricted to yeast Prx1 as human PRXD6, targeted to the yeast mitochondrial matrix, also very efficiently elicited GSSG formation upon treatment of cells with H 2 O 2

This means that it mimics the action of BDNF by binding to the same receptor in the brain as natural BDNF

Once captured and neutralized by glutathione, these elements can be safely eliminated through the liver and gut

However, its essential to remember that using glutathione for cosmetic purposes, such as skin lightening, is a relatively new application and requires careful consideration