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Comparing metformin with sulfonylureas is clinically sensible because both are common firstline options in diabetes history, yet they act through very different mechanisms
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Nutrient Bioavailability: Some research suggests that delayed digestion may reduce the absorption efficiency of certain micronutrients, such as fat-soluble vitamins (A, D, E, and K), which require bile and proper fat metabolism for uptake
Research suggests that they have protective effects on the liver, demonstrating the potential for fibrosis regression and improved survival rates in patients with advanced liver disease
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