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doi:10.1007/7081_2015_176
Purity standards of 98% or higher via HPLC are appropriate for research use, with mass spectrometry confirmation of the correct molecular weight (9111.5 Da) recommended
Three studies with 295 exposed pregnancies and 100,239 comparator pregnancies found no significant increase in small-for-gestational-age births (OR 0.84
Studies suggest the prevalence of deficiency in the UK is one in 10 people aged 75 and over, one in 20 aged 65-74, and lower in younger age groups except for vegans, where prevalence is around 11%
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