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Because it targets two pathways instead of one, clinical data often shows a higher average percentage of weight loss compared to single-agonist medications
NHS and NICE Guidance on Post-Bariatric Weight Management NICE and BOMSS recommend long-term specialist MDT follow-up after bariatric surgery, with weight management supported through evidence-based diet, physical activity, and behavioural support
The side effect profiles also differ between oral and injectable forms
Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration
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