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We interrogated gene expression changes in more detail focusing on pathways involved in cellular glucose handling: Glycolysis, TCA Cycle, Oxidative Phosphorylation ( Figures 5DF )
Work from our and other groups suggested LAC as a novel epigenetic modulator of brain plasticity and a therapeutic target for clinical phenotypes of depression linked to childhood trauma
At the same time, it controls the amount of a growth hormone inhibiting hormone (GHIH), known as somatostatin, which downregulates pituitary GH secretion
Many adults aiming for weight management benefit from ~1.21.6 g protein/kg/day (individualize with your clinician)
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