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DSIP readily crosses the blood-brain barrier to exert central effects and may enhance inhibitory neuronal activity or modulate sleep-regulating brain regions
AOD-9604 does not cause receptor desensitization or hormonal suppression, so the break is precautionary rather than biologically required
Model-simulated concentration profiles demonstrated that at steady state, single deviations from the oral semaglutide recommended dosing conditions have a minimal impact on exposure
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