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*Correspondence: Dong-Dong Wang [email protected] He [email protected] Wang [email protected] These authors have contributed equally to this work This article was submitted to Clinical Nutrition, a section of the journal Frontiers in Nutrition Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
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As previously described under the subsection of IGF-1R, the authors investigated the let-7 function in glucose metabolism using inducible let-7 transgenic mice model and found that let-7 overexpression induced glucose intolerance by targeting multiple components of the insulin-PI3K-mTOR signaling pathway including IRS-2, IGF-1R, and INSR
An Moreover, an analysis of 29 human studies found that taking a vitamin C supplement reduced systolic blood pressure (the upper value) by 3.8 mmHg and diastolic blood pressure (the lower value) by 1.5 mmHg, on average, in participants with normal or high blood pressure
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