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Methods Plasmid construction The Exe4 gene was codon-optimized using the GeneSmart codon optimization tool ( based on the amino acid sequence in existing publication (Supplementary Table 1)

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L-carnitine also plays an imperative role in the regulation of metabolic signaling pathways involved in muscle protein balance, proteolysis and muscle protein synthesis

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A number of studies indicate the role of angiotensin II (Ang II) in the activation of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (Dikalov and Nazarewicz 2013

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