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Increased understanding has revealed that the roles of these metabolic pathways are not limited to cellular energetics, but they are also involved in the assembly of the most important cellular building blocks, including nucleotides and amino acids (Zhang et al., 2008)
Turetsky BI, Calkins ME, Light GA, Olincy A, Radant AD, Swerdlow NR (2007)
In summation, GGCs potential to elevate intracellular glutathione levels above homeostasis in an energy-efficient manner, makes it a promising candidate as a potential therapeutic for mitochondrial diseases
The negative consequences are primarily divided into two categories: the first is caused by mitochondrial oxidative stress, which includes cancer, neurodegeneration, diabetes, chronic illnesses, and aging
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