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Although extremely rare overall, carcinomas of lactotroph origin represent 30% of all pituitary carcinomas and are the most common type 77,142
12 In contrast, no benefit of GLP-1 RAs was observed in terms of all-cause death, HF hospitalisation or cardiovascular death
In fact, a 2024 EMA Pharmacovigilance Risk Assessment Committee (PRAC) review concluded that there is no causal association between GLP-1 receptor agonists and suicidal thoughts or self-harm
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