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Unlike pair-fed rats (rats that ate the same amount of food as the tesofensine-treated rats), the rats treated with tesofensine did not regain their weight, suggesting that tesofensine may increase energy expenditure

People following a structured eating plan alongside GLP-1 support should prioritize prebiotic fiber sources to amplify this pathway naturally

Seek prompt medical advice if insomnia persists beyond three to four weeks, or if new palpitations, severe abdominal pain, or signs of obstructive sleep apnoea develop

Transdermal patches: Develop non-invasive drug delivery methods to improve patient compliance