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( A ) Schematic of the mouse study design
L-glutathione is present in every cell of your body, but it is found in particularly high concentrations in the liver
5 Conclusion Collectively, it can be concluded that MTX-induced hepatotoxicity is mediated, at least in part, through ER stress, which was confirmed by the reversal of MTX toxicity upon administration of 4-PBA and NAC
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