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Diarrhoea is most pronounced during the dose-escalation phase
In addition, gene sets from Reactome Pathway Database were selected and GSEA was performed using the R package clusterProfiler
A doubled dose can also cause acute pancreatitis, a painful inflammation of the pancreas that requires emergency care
Retatrutides safety profile is consistent with whats already been observed GLP-1 receptor agonists and combined GLP-1/GIP receptor agonists, meaning the expected side effects are primarily gastrointestinal (GI) in nature: Nausea, vomiting, diarrhea, and constipation
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