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In the DUAL V, 40% of patients assuming Liraglutide/Degludec received 50 dose steps after 26 weeks corresponding to 1.8 mg of Liraglutide, with a wide range of variability also depending on baseline BMI (65)

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Physiologically, ovulation requires: Pulsatile GnRH secretion from the hypothalamus Release of FSH and LH from the anterior pituitary Follicular maturation and estradiol production Mid-cycle LH surge leading to ovulation Disruption at any level of this axis can result in anovulation

Together, these peptides target different pathways in the body, promoting comprehensive and efficient tissue repair