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In contrast, PG-102 achieved a ~450 mg/dL glucose reduction and ~5% HbA1c decrease by 2-months, restoring normoglycemia and maintaining efficacy throughout the 3-month study (Fig

Tirzepatide: Effective but Requires Lifestyle Support Studies of tirzepatide have shown its effectiveness in treating type 2 diabetes and in promoting significant weight loss in obese individuals

Downregulation of GLP-1 and GIP receptor expression by hyperglycemia: possible contribution to impaired incretin effects in diabetes

If you're generally healthy and don't have any pre-existing medical conditions, GLP-1 supplements may seem like a harmless addition