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Recent guidance from endocrinology societies emphasizes the importance of tailoring therapy to individual risk profiles, including cardiovascular and renal considerations
One of the mechanisms supporting this resistance is the interaction between FOXO4 and p53 within the nucleus
Retatrutide is an investigational triple receptor agonist developed by Eli Lilly that targets GLP-1, GIP, and glucagon receptors, giving it a broader metabolic mechanism than single- or dual-pathway therapies
The aforementioned studies indicate that a ferroptosis inducer may serve as a promising pharmaceutical agent for the treatment of GC
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