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Pull back by 50 to 100 calories and wait two weeks before adjusting again
The two isomers have opposing pharmacological profiles: enclomiphene is a pure estrogen receptor antagonist centrally, while zuclomiphene has partial agonist activity that can suppress the HPG axis
Chronic sleep restriction raises hunger and can blunt dietary adherence
Conversely, IR contributes to reduced dopamine transporter expression coupled with increased excitatory glutamatergic input, elevating extracellular dopamine levels
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