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Pan-drug resistance and hypervirulence in a human fungal pathogen are enabled by mutagenesis induced by mammalian body temperature
For example, the treatment with acetyl-l-carnitine induced haeme oxygenase enzyme in rat astrocytes in a dose- and time-dependent fashion, heat shock protein 60 upregulation, and increased expression of the nuclear factor erythroid 2-related factor 2 transcription factor, a master regulator of antioxidant proteins [18]
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