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After that, the dose is gradually increased over several months, usually moving up through 0.5 mg, 1.0 mg, and 1.7 mg, until reaching the full 2.4 mg dose once per week, the standard maintenance dose for ongoing weight-loss support
Risk- benefit of treating LM In Strategies for reducing final surgical defect sizes in the treatment of lentigo maligna, Sampson and Bowen (Derm Surg April 2020 46 4 537-43) speculate that the risk of death corresponds to a 99.91% survival rate at 10 years for locally recurrent LM or approximately 1 death in 10,000 (Staged excision of LM then recurrence 5.9% x these recurring as stage IA MM 22.6% x 7% risk of death at 10 years from stage IA = 0.09%)
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69% have been using the medication for fewer than two years and 53% expect to discontinue use in less than two more years 77% who had discontinued a GLP-1 medication said they were satisfied with the weight loss they experienced, but 90% were on the drug for less than one year Primary barriers to continued use: 76% note side effects
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