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For 3D cultures, Promega recommends CellTiter-Glo 3D Cell Viability Assay, which uses an enhanced lysis buffer specifically formulated to penetrate 3D tumor spheroid structures and release ATP from cells throughout the spheroid
Over a year, thats $6,000-$12,000 in savings
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Mongongu C, Coudore F, Domergue V, et al
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