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Description

Although the observed increase in risk is small on an individual level, the broad adoption of GLP1-RAs for weight management amplifies its potential implications at the population level, underscoring the need for heightened awareness among clinicians and patients about the dermatologic effects of these medications, the authors wrote

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Specifically, it is manifested as a decrease in the mitochondrial DNA content, a reduction in the activity of electron transport chain complexes (such as complexes I and II), and a weakened ability to generate ATP, a key product of cellular energy metabolism [30]

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Amino acid sequence specificity: It is highly homologous to the 177-191 amino acids of a certain chemical, but the lipolysis activity has been optimized through chemical modification

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This is called step therapy

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