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Human erythroid differentiation requires VDAC1-mediated mitochondrial clearance

Cezard JP, Forgue-Lafitte ME, Chamblier MC, Rosselin GE

Furthermore, the SLC7A11 gene, which is often significantly downregulated in PD, is also considered a critical regulator of ferroptosis and can protect dopaminergic neurons by activating the transsulfuration pathway, indicating a potential interplay with DJ-1 (93)

A clinical review of the patient case should still take place prior to consideration of switching where a clinical decision should be made as to whether a GLP-1 RA or GIP/GLP-1 RA is the most appropriate choice in the circumstances