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Animal studies suggest that cochlear synaptopathydefined as the loss of synapses between IHCs and auditory nerve fibersmay contribute specifically to central auditory hyperactivity and tinnitus following noise exposure 41

2009 in PNAS (PMC2667044) showed stress suppressed preproglucagon (PPG) mRNA in rat NTS neurons within 30 minutes via a glucocorticoid-dependent mechanism