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Metformin, through activation of the AMPK/PGC-1 cascade, reduces A and tau pathology, restores hippocampal neurogenesis, and improves recognition memory, thereby capturing the metabolic and neurogenic dimensions of exercise [252]
In our investigations, we observed that robust angiogenesis, characterized by grossly visible neovascularization and a marked increase in CD31-positive luminal structures by immunohistochemistry, was a prominent histological feature of healing in animal models of tissue injury treated with BPC157
doi: 10.3390/tropicalmed4010040 4 HotezPJAlvaradoMBasanezMGBolligerIBourneRBoussinesqMet al
Their pivotal role in the pathogenesis of numerous diseases underscores their significance
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