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Your basal metabolic rate (BMR) decreases proportionally with weight loss, meaning the calorie deficit that initially produced weight loss may no longer be sufficient
Metformin, while also unlikely to be covered by insurance for weight loss purposes, is much more affordable due to generic options
Endogenous hyperinsulinemia may cause weight gain and obesity [30], and treatment with insulin causes substantial weight gain, and may even increase cardiovascular risk [31]
Storage: e.g., 20 C (protect from light) Stability: Lyophilized form remains stable when stored under recommended conditions
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![Structures of (a) GLP-1, (b) GIP and (c) tirzepatide [19, 88, 90]](https://www.researchgate.net/publication/370926483/figure/fig4/AS:11431281185432337@1693619320519/Structures-of-a-GLP-1-b-GIP-and-c-tirzepatide-19-88-90-Amino-acids-are.png)
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