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Hum Brain Mapp
Protection of the Gastrointestinal Tract : BPC-157 has demonstrated protective effects in experimental models of gastric ulcers, intestinal inflammation, and colitis
The integrated PK-PD findings, including nonlinear exposure, target tissue accumulation, and disruption of L-carnitine homeostasis, collectively elucidate mildronates mechanism of action through energy substrate depletion, as well as its intrinsic efficacy-toxicity duality
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